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Page 1
Molybdenum Cofactor Deficiency in Humans.
Johannes L, Fu CY, Schwarz G. Johannes L, et al. Molecules. 2022 Oct 14;27(20):6896. doi: 10.3390/molecules27206896. Molecules. 2022. PMID: 36296488 Free PMC article. Review.
Molybdenum cofactor (Moco) deficiency (MoCD) is characterized by neonatal-onset myoclonic epileptic encephalopathy and dystonia with cerebral MRI changes similar to hypoxic-ischemic lesions. ...In the absence of a specific treatment for MoCD type B/C and SOX defi …
Molybdenum cofactor (Moco) deficiency (MoCD) is characterized by neonatal-onset myoclonic epileptic encephalopathy and dystoni …
Molybdenum cofactor biology, evolution and deficiency.
Mayr SJ, Mendel RR, Schwarz G. Mayr SJ, et al. Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118883. doi: 10.1016/j.bbamcr.2020.118883. Epub 2020 Oct 2. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33017596 Free article. Review.
The molybdenum cofactor (Moco) represents an ancient metal-sulfur cofactor, which participates as catalyst in carbon, nitrogen and sulfur cycles, both on individual and global scale. ...
The molybdenum cofactor (Moco) represents an ancient metal-sulfur cofactor, which participates as catalyst in carbon, nitrogen and su …
Mechanistic insights into the treatment of iron-deficiency anemia and arthritis in humans with dietary molybdenum.
Grech BJ. Grech BJ. Eur J Clin Nutr. 2021 Aug;75(8):1170-1175. doi: 10.1038/s41430-020-00845-7. Epub 2021 Jan 29. Eur J Clin Nutr. 2021. PMID: 33514867 Review.
Molybdenum forms part of the active site of these enzymes. Despite this, it is unlikely that a molybdenum deficiency can develop in humans that are on an oral diet and not exposed to unsafe levels of a molybdenum antagonist. ...The examination of these …
Molybdenum forms part of the active site of these enzymes. Despite this, it is unlikely that a molybdenum deficiency ca …
Essential metals in health and disease.
Jomova K, Makova M, Alomar SY, Alwasel SH, Nepovimova E, Kuca K, Rhodes CJ, Valko M. Jomova K, et al. Chem Biol Interact. 2022 Nov 1;367:110173. doi: 10.1016/j.cbi.2022.110173. Epub 2022 Sep 22. Chem Biol Interact. 2022. PMID: 36152810 Free article. Review.
Among those metals that are currently considered to be essential for normal biological functioning are four main group elements, sodium (Na), potassium (K), magnesium (Mg), and calcium (Ca), and six d-block transition metal elements, manganese (Mn), iron (Fe), cobalt (Co), copper …
Among those metals that are currently considered to be essential for normal biological functioning are four main group elements, sodium (Na) …
Molybdenum.
Barceloux DG. Barceloux DG. J Toxicol Clin Toxicol. 1999;37(2):231-7. doi: 10.1081/clt-100102422. J Toxicol Clin Toxicol. 1999. PMID: 10382558 Review.
Molybdenum rapidly polymerizes to a wide variety of complex polymolybdate compounds in solution. ...Molybdenosis (teart) is a form of molybdenum toxicity that produces a disease in ruminants similar to copper-deficiency. ...
Molybdenum rapidly polymerizes to a wide variety of complex polymolybdate compounds in solution. ...Molybdenosis (teart) is a form of …
Genetics of molybdenum cofactor deficiency.
Reiss J. Reiss J. Hum Genet. 2000 Feb;106(2):157-63. doi: 10.1007/s004390051023. Hum Genet. 2000. PMID: 10746556 Review.
Molybdenum cofactor (MoCo) deficiency leads to a combined deficiency of the molybdoenzymes sulphite oxidase, xanthine dehydrogenase and aldehyde oxidase. Effective therapy is not available for this rare disease, which results in neonatal seizures and other ne …
Molybdenum cofactor (MoCo) deficiency leads to a combined deficiency of the molybdoenzymes sulphite oxidase, xanthine d …
The molybdenum cofactor.
Mendel RR. Mendel RR. J Biol Chem. 2013 May 10;288(19):13165-72. doi: 10.1074/jbc.R113.455311. Epub 2013 Mar 28. J Biol Chem. 2013. PMID: 23539623 Free PMC article. Review.
The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalyti …
The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound …
Molybdenum cofactor deficiency.
Arnold GL, Greene CL, Stout JP, Goodman SI. Arnold GL, et al. J Pediatr. 1993 Oct;123(4):595-8. doi: 10.1016/s0022-3476(05)80961-8. J Pediatr. 1993. PMID: 8410516
We describe a new case of molybdenum cofactor deficiency, an underrecognized inborn error of metabolism that results in neonatal seizures and neurologic abnormalities. ...
We describe a new case of molybdenum cofactor deficiency, an underrecognized inborn error of metabolism that results in neonat …
Does the Micronutrient Molybdenum Have a Role in Gestational Complications and Placental Health?
Foteva V, Fisher JJ, Qiao Y, Smith R. Foteva V, et al. Nutrients. 2023 Jul 27;15(15):3348. doi: 10.3390/nu15153348. Nutrients. 2023. PMID: 37571285 Free PMC article. Review.
Molybdenum is an essential trace element for human health and survival, with molybdenum-containing enzymes catalysing multiple reactions in the metabolism of purines, aldehydes, and sulfur-containing amino acids. ...Although the benefits of molybdenum as an a …
Molybdenum is an essential trace element for human health and survival, with molybdenum-containing enzymes catalysing multiple …
Molybdenum-cofactor deficiency: CT and MR findings.
Schuierer G, Kurlemann G, Bick U, Stephani U. Schuierer G, et al. Neuropediatrics. 1995 Feb;26(1):51-4. doi: 10.1055/s-2007-979720. Neuropediatrics. 1995. PMID: 7791952
We describe the CT and MR findings in molybdenum-cofactor deficiency, a rare metabolic disorder which is caused by the defect of a molybdenum-containing enzyme cofactor. ...The abnormal shape of the frontal horns, although possibly not specific, may even sugg …
We describe the CT and MR findings in molybdenum-cofactor deficiency, a rare metabolic disorder which is caused by the defect …
1,144 results